Janusonis Lab
Our interdisciplinary research program investigates the dynamics and self-organization of the brain serotonergic axons. These axons weave through neural tissue in meandering trajectories and are a core component of biological neural networks, from humans to sharks. In virtually all brain regions, serotonergic axons produce massive but poorly understood fiber meshworks that control neuroplasticity, perception, emotions, the sleep-wake cycle, and other functions. Our experimental toolbox includes transgenic animal models, advanced microscopy, neuronal cell cultures, and comparative neurobiology. We build predictive brain models based on the theory of stochastic processes, in collaboration with physicists and mathematicians.
