Our laboratory studies the brain serotonin matrix and its interactions with other cellular elements. Serotonin molecules are ancient signal carriers that control the behavior of a shark, the cognition of a human, and many other vertebrate neuroprocesses. In particular, we are interested in the stochastic organization of serotonin-releasing axons and their functional relationships with microglia and blood platelets. Some of these problems have immediate clinical relevance: nearly all mental disorders have been associated with dysfunction in serotonin signaling, and the platelet hyperserotonemia of autism remains an enigma after half a century of research. Our research is inherently interdisciplinary and spans molecular neurobiology, advanced microscopy, ex vivo neuronal systems, comparative neuroanatomy, and the mathematics of stochastic processes. We are funded by the National Science Foundation, the National Institute of Mental Health, and the California NanoSystems Institute.